BP301T. Pharmaceutical Organic Chemistry 2 ( Syllabus )

 BP301T. Pharmaceutical Organic Chemistry 2

Pharmaceutical Organic Chemistry 2


Pharmaceutical Organic Chemistry 2

UNIT - I

Benzene and it's derivatives 

      A. Analytical, synthetic and other evidences in the derivation of structure of                             benzene, Orbital picture, resonance in benzene, aromatic characters, Huckel's  rule              (coming soon)

        B. Reactions of benzene - nitration,  sulphonation, halogenation-reactivity,                                  Friedelcrafts alkylation-  reactivity,  limitations, Friedelcrafts acylation.                                (coming soon)

        C. Substituents, effect of substiuents on reactivity and orientation of mono substituted               benzene compounds towards electrophilic substitution reaction (coming soon)

        D. Structure and uses of DDT, Saccharin, BHC and Chloramine (coming soon)


UNIT - II

    Phenols* - Acidity of phenols, effect of substituents on acidity, qualitative tests,                         Structure     and uses of phenol, cresols, resorcinol, naphthols (coming soon)

    Aromatic Amines* -  Basicity of amines, effects of substituents on basicity, and                         synthetic     uses of aryl diazonium salts (coming soon)

    Aromatic Acids* -  Acidity, effect of substituents on acidity and important reactions of            benzoic acid. (coming soon)

UNIT - III

Fats and Oils

    A. Fatty acids - reactions. (coming soon)

    B. Hydrolysis, Hydrogenation, Saponification and Rancidity of oils, Drying oils. (coming soon)

    C. Analytical constants - Acid value, Saponification value, Ester value, Iodine value, Acetyl value,             Reichert Meissl (RM) value - significance and principle involved in their                                               determination.  (coming soon)

UNIT - IV

Polynuclear hydrocarbons: 

    A. Synthesis, reactions (coming soon)

    B. Structure and medicinal uses of Naphthalene, Phenanthrene, Anthracene, Diphenylmethane,                   Triphenylmethane and their derivatives (coming soon)

UNIT - V 

    Cyclo alkanes*

       stabilities - Baeyer's strain theory, limitation of Baeyer's strain theory, Coulson and Moffitt's                   modification, Sachse Mohr's theory (Theory of strainless rings), reactions of cyclopropane and               cyclobutane only   (coming soon)




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